A Review of Diabetic Kidney Disease

Review Article

J Fam Med. 2017; 4(2): 1111.

A Review of Diabetic Kidney Disease

Chan S1,2*, Chan HP² and Baboolal K1,2

¹Kidney Health Service, Metro North Hospital and Health Service, Brisbane, Queensland, Australia

²School of Medicine, The University of Queensland, Brisbane, Queensland, Australia

*Corresponding author: Samuel Chan, Kidney Health Service, Metro North Hospital and Health Service, Brisbane, Queensland, School of Medicine, The University of Queensland, Brisbane, Queensland, Australia

Received: February 08, 2017; Accepted: March 02, 2017; Published: March 03, 2017

Abstract

A 41-year-old obese male presented with rapid weight gain (7kg in one week) associated with bilateral oedema to the knees. He had nephrotic range proteinuria of 9 grams per day with impaired kidney function, serum creatinine 176umol/L. He was diagnosed with Type II Diabetes Mellitus (HbA1C 12.1%) and renal biopsy confirmed class III diabetic nephropathy with nodular glomeurlosclerosis.

Introduction

The incidence and prevalence of diabetes mellitus have grown significantly throughout the world, primarily due to the increasing prevalence of Type II Diabetes Mellitus [1]. This increase in the number of people developing diabetes has had a major impact on the development of diabetic kidney disease (DKD). Although kidney disease attributable to diabetes is referred to as DKD, diabetes and various kidney diseases are common chronic conditions. Thus, people with diabetes may have other aetiologies of chronic kidney disease (CKD) in addition to diabetes. Notably, DKD remains one of the most frequent complications of both types of diabetes, and diabetes is the leading cause of end-stage kidney disease (ESKD), accounting for approximately 50% of cases in the developed world (Figure 1).

Citation: Chan S, Chan HP and Baboolal K. A Review of Diabetic Kidney Disease. J Fam Med. 2017; 4(2): 1111. ISSN:2380-0658